CD3 is a component of T cell surface receptor (TCR), it cantains 5 invariable chains: gamma- , delta-, epsilon-, and zeta/eta Clevers et al. (1988) showed the TCR/CD3 complex consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits,CD3 is responsible for the signal transduction of the TCR.
Aliases: T3Z; CD3H; CD3Q; CD3Z; TCRZ; CD3-ZETA; CD247
Entrez GeneID: 919
Swissprot: P20963
Host/Isotype: Mouse IgG2a
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human CD3 expressed in E. Coli.