This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Aliases:    TREM1; TREM-1    

Entrez GeneID:    54210    

Swissprot:    Q9NP99     

WB Predicted band size :   26.4kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity :   Human,Rat,Monkey    

Immunogen :   Purified recombinant fragment of human CD354 (AA: extra 21-205) expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000