This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Aliases : TREM1; TREM-1
Entrez GeneID: 54210
Swissprot: Q9NP99
WB Predicted band size: 26.4kDa
Host/Isotype: Mouse IgG2a
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human CD354 (AA: extra 21-205) expressed in E. Coli.
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