The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. 

Aliases：    CD30; Ki-1; D1S166E; TNFRSF8    

Entrez GeneID：    943    

Swissprot：    P28908    

Host/Isotype：    Mouse IgG1    

Species Reactivity ：   Human    

Immunogen ：   Purified recombinant fragment of human CD30 expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000