This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Aliases : FCRL2; FCRH2; IFGP4; IRTA4; SPAP1; SPAP1A; SPAP1B; SPAP1C
Entrez GeneID: 79368
Swissprot : Q96LA5
WB Predicted band size: 55.5kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen : Purified recombinant fragment of human CD307B (AA: extra 20-253) expressed in E. Coli.