The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

Aliases :   NCR3; 1C7; MALS; LY117; NKp30    

Entrez GeneID:    259197    

Swissprot:    O14931       

WB Predicted band size :   21.5kDa    

Host/Isotype:   Mouse IgG1    

Species Reactivity :   Human, Mouse, Rat    

Immunogen :   Purified recombinant fragment of human CD337 (AA: extra 19-135) expressed in HEK293-6e cells supernatant.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000