This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

Aliases:    FZD4; Fz4; EVR1; FEVR; Fz-4; FzE4; GPCR; hFz4; FZD4S    

Entrez GeneID:    8322    

Swissprot:    Q9ULV1      

WB Predicted band size :   60kDa    

Host/Isotype :   Mouse IgG1    

Species Reactivity :   Human    

Immunogen:    Purified recombinant fragment of human CD344 (AA: extra 37-222) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000