The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Aliases: FCGR2B;CD32; FCG2; CD32B; FCGR2; IGFR2; FCGR2C; FcRII-c
Entrez GeneID: 2213
Swissprot: P31994
WB Predicted band size: 34kDa
Host/Isotype: Mouse IgG1
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human CD32B (AA: 43-217) expressed in E. Coli.