This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases:    KN; C3BR; C4BR    

Entrez GeneID:    1378    

Swissprot:    P17927    

WB Predicted band size :   161.7kDa    

Host/Isotype :   Mouse IgG1    

Species Reactivity :   Human    

Immunogen:    Purified recombinant fragment of human CD35 expressed in E. Coli.    

IHC    1/100 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000