Chemical Name: Sodium polyoxyethylene(1) lauryl sulfate. It is a white to pale yellow, slightly viscous substance classified as an anionic surfactant. It is readily soluble in water, exhibits good compatibility with other anionic and non-ionic surfactants, and possesses excellent emulsifying, foaming, solubilizing, and detergency properties.
•Strong Detergency and Solubilizing Power: Lyses cell membranes or solubilizes hydrophobic targets (e.g., lipoproteins, membrane-bound antigens) to release target analytes.
•Emulsion Stability: Maintains the dispersibility of latex/colloidal gold particles, preventing signal inhomogeneity caused by aggregation (e.g., in latex-enhanced immunoturbidimetric assays).
•Low Foaming: Reduces foam interference during reagent handling (e.g., automated pipetting), ensuring detection accuracy.
•Formulation Compatibility: Can be used synergistically with other anionic/non-ionic surfactants (e.g., Triton X-100) and blocking agents (e.g., BSA) to optimize system balance.
•Mild Protein Denaturation: At controlled concentrations, it can partially denature proteins to expose hidden epitopes, enhancing antibody binding efficiency (e.g., in ELISA sample diluents).
•Sample Pretreatment Solution: Added to blood/urine lysis buffers to dissolve cells or micellize lipids, reducing matrix interference.
•Latex Particle Stabilizer: Pre-mixed in latex microparticle suspensions to prevent particle aggregation via electrostatic repulsion, enhancing the stability of turbidimetric signals.
•Colloidal Gold Conjugate Reconstitution Solution: Used in combination with Bovine Serum Albumin (BSA) to reduce non-specific adsorption of gold-labeled antibodies, lowering background values.
•Wash Buffer: Used in ELISA/chemiluminescence wash buffers to gently remove unbound substances while preserving weakly bound signals.
•Solubilizer: Dissolves hydrophobic reagents (e.g., in fat-soluble vitamin detection) to improve reaction homogeneity.
Standapol® is a trademark of BASF.