AccuSift provides high-performance polymyxin B competitive assay pairings, characterized by exceptional batch-to-batch consistency and optimized for IVD kit development (Lateral Flow, Chemiluminescence, ELISA, POCT). These pairings offer high affinity and specificity, facilitating rapid detection.Polymyxin B is an antibiotic that inhibits various Gram-negative bacteria, including Pseudomonas aeruginosa, Escherichia coli, Klebsiella, and Haemophilus. It remains effective against strains resistant to other antibiotics. However, due to its severe nephrotoxicity and neurotoxicity, it is reserved for short-term critical care in burn patients with sepsis or for topical spray/irrigation. Intravenous administration is prohibited to avoid respiratory failure. The drug can be formulated as a topical solution with normal saline.Performance Characteristics:
Sensitivity: ELISA IC50: 20 ppb; Colloidal Gold: 500 ppb
Source: Mouse Monoclonal Antibody
Recommended Pairing: (Coating) / (Labeling)
Storage: Long-term storage at ≤ –20°C; short-term storage at 2–8°C. Shipped on ice packs.