AccuSift provides high-performance tetracycline-class competitive assay pairings, characterized by exceptional batch-to-batch consistency and optimized for IVD kit development (Lateral Flow, Chemiluminescence, ELISA, POCT). These pairings offer high affinity and specificity, facilitating rapid detection.Tetracyclines are a class of broad-spectrum antibiotics, primarily including chlortetracycline, oxytetracycline, and tetracycline. They share a common chemical core structure. Chlortetracycline and oxytetracycline are derivatives of tetracycline; the former is chlorotetracycline, and the latter is oxytetracycline. All tetracyclines are amphoteric compounds.They inhibit most Gram-positive and Gram-negative bacteria, exhibit bactericidal effects at high concentrations, and are effective against Rickettsia, Chlamydia trachomatis, and other pathogens, with particularly strong activity against Gram-negative bacilli. Their mechanism of action involves preventing aminoacyl-tRNA from binding to the ribosomal subunit, thereby inhibiting peptide chain elongation and protein synthesis, which suppresses bacterial growth. High concentrations can also exert bactericidal effects.
Sensitivity: ELISA IC50: 0.2 ppb; Colloidal Gold: 2 ppb
Cross-Reactivity: TC 0.2 ppb; OTC 0.2 ppb; DC 0.2 ppb; CTC 0.3 ppb
Sensitivity: ELISA IC50: 0.5 ppb; Colloidal Gold: 5 ppb
Cross-Reactivity: TC 0.5 ppb; OTC 0.5 ppb; DC 0.5 ppb; CTC 1 ppb
Sensitivity: ELISA IC50: 0.5 ppb; Colloidal Gold: 5 ppb
Cross-Reactivity: TC 0.5 ppb; OTC 0.5 ppb; DC 1 ppb; CTC 1 ppb
Source: Mouse Monoclonal Antibody
Recommended Pairing: (Coating) / (Labeling)
Storage: Long-term storage at ≤ –20°C; short-term storage at 2–8°C. Shipped on ice packs.
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