Ovalbumin (OVA), designated as Gal d 2, is the most abundant protein in egg white and ranks among the predominant allergens in egg allergies. As a glycoprotein with a molecular weight of approximately 43 kDa, OVA accounts for about 54% of the total protein content in egg white. It is the earliest identified and most extensively studied allergenic component in eggs. Beyond its role as a natural allergen, it is widely utilized as a model antigen for investigating allergic reaction mechanisms and constructing immunological experimental models.
Upon ingesting food containing ovalbumin, atopic individuals experience a misidentification of the protein by their immune system as a harmful substance, stimulating the production of OVA-specific IgE antibodies. Upon subsequent exposure to OVA, these IgE antibodies rapidly bind to mast cells and basophils, triggering the release of inflammatory mediators such as histamine and leukotrienes, thereby provoking allergic reactions.
AccuSift offers high-performance Anti-Ovalbumin Antibody Pairs, optimized for IVD kit development (including Lateral Flow Assays, Chemiluminescence, ELISA, and POCT). Featuring high affinity, high specificity, and excellent batch-to-batch consistency, these pairs enable rapid and reliable detection.
Sensitivity: ELISA LOD: 0.1 ppb
Source: Mouse Monoclonal
Purity: ≥ 90%
Recommended Pair: (Coating) / (Labeling)
Storage & Shipping: Long-term storage at ≤ -20°C; short-term storage at 2-8°C. Shipped with ice packs.