β-Conglycinin is the major component of the soybean 7S globulin fraction and ranks among the predominant soybean allergens, officially designated as Gly m 5. Accounting for approximately 30% of the total soybean seed protein, it is a trimeric glycoprotein with a molecular weight ranging from 140 to 180 kDa. It is composed of three subunits—α (67 kDa), α′ (71 kDa), and β (50 kDa)—held together by hydrophobic interactions and electrostatic forces.

This protein exhibits exceptional thermal stability and strong immunogenicity. The α subunit is recognized by the sera of approximately 23% of soybean allergy patients, and all three subunits demonstrate varying degrees of allergenicity. As an allergen, β-conglycinin can enter the gut mucosa in a partially undegraded macromolecular form, triggering both IgE-mediated immediate hypersensitivity reactions and delayed-type hypersensitivity reactions. Furthermore, the Soymetide tridecapeptide located within the α′ subunit can directly activate immune receptors to initiate immune responses.

AccuSift offers high-performance Anti-β-Conglycinin Antibody Pairs, optimized for IVD kit development (including Lateral Flow Assays, Chemiluminescence, ELISA, and POCT). Featuring high affinity, high specificity, and excellent batch-to-batch consistency, these pairs enable rapid and reliable detection.

Sensitivity: ELISA LOD: 1 ppb

Source: Mouse Monoclonal

Purity: ≥ 90%

Recommended Pair: (Coating) / (Labeling)

Storage & Shipping: Long-term storage at ≤ -20°C; short-term storage at 2-8°C. Shipped with ice packs.