Staphylococcal Enterotoxin D (SED) is a heat-stable protein toxin secreted by Staphylococcus aureus. As a D serotype of staphylococcal enterotoxins, it is one of the most common causative agents of staphylococcal food poisoning.

SED is an exotoxin encoded by a gene located on the chromosome of Saphylococcus aureus, with plasmid-borne proteins capable of activating toxin expression. It is one of the eight classic serotypes (A, B, C1, C2, C3, D, E, F). Under suitable temperature conditions, SED is readily produced in large quantities in foods rich in protein and starch. Common high-risk contaminated foods include dairy products, ready-to-eat meats, leftover rice, and chilled processed cakes.

The toxin acts directly on the enteric nervous system; upon binding to neural receptors in the gut, it stimulates the vomiting center, leading to acute gastroenteritis. Compared to other serotypes, SED is the third most common cause of staphylococcal food poisoning (after Type A and Type C). It is classified as a preformed toxin; therefore, ingestion leads to rapid onset of illness without requiring the presence of viable bacteria in the host.

AccuSift offers high-performance Anti-Staphylococcal Enterotoxin D Antibody Pairs, optimized for IVD kit development (including Lateral Flow Assays, Chemiluminescence, ELISA, and POCT). Featuring high affinity, high specificity, and excellent batch-to-batch consistency, these pairs enable rapid and reliable detection.

Sensitivity: ELISA IC50: 0.5 ppb; Lateral Flow Assay: 1 ppb

Source: Mouse Monoclonal

Purity: ≥ 90%

Recommended Pair: (Coating) / (Labeling)

Storage & Shipping: Long-term storage at ≤ -20°C; short-term storage at 2-8°C. Shipped with ice packs.