CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.
Aliases： MAL; p32; Leu2; CD8A
Entrez GeneID： 925
Swissprot： P01732
Host/Isotype： Mouse IgG1
Species Reactivity ： Human
Immunogen ： Purified recombinant fragment of human CD8 expressed in E. Coli.
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