This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: TP120; FLJ44171
Entrez GeneID: 923
Swissprot : P30203
WB Predicted band size: 71.8kDa
Host/Isotype: Mouse IgG1
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human CD6 (AA: 472-668) expressed in E. Coli.