This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

Aliases ：   SELP; CD62; GRMP; PSEL; GMP140; LECAM3; PADGEM    

Entrez GeneID ：   6403    

Swissprot：   P16109     

WB Predicted band size：    90.8kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen ：   Purified recombinant fragment of human CD62P (AA: extra 42-208) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000