This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
Aliases : Bcl-2; PPP1R50
Entrez GeneID: 596
Swissprot : P10415
WB Predicted band size: 26.3kDa
Host/Isotype : Mouse IgG2b
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human BCL2 (AA: 1-239) expressed in E. Coli.
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