Protein L is a multi-domain protein found on the surface of Peptostreptococcus magnus, also known as Peptostreptococcus magnusProtein L (PPL). Unlike Protein A or Protein G, Protein L primarily binds to the kappa light chains of antibodies without interfering with the antigen-binding site. This unique binding mechanism enables Protein L to interact with a broader range of antibody classes and subtypes, including human IgG, IgM, IgA, and IgD containing kappa light chains, as well as mouse IgG and IgM, rat IgG, Fab fragments, single-chain variable fragments (ScFv), and more. The recombinant Protein L is engineered by expressing five antibody-binding domains derived from the native protein, retaining the complete antibody-binding functionality of natural Protein L.
Source: Escherichia coli
Molecular Weight: 41.5 kDa
Isoelectric Point (pI): 4.86
Purity: ≥ 95% (SDS-PAGE)
Form: Lyophilized
Solubility: Soluble in distilled water at ≥ 10 mg/mL
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