Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

Aliases：    HIST2H3A;H3/n; H3/o    

Entrez GeneID ：   333932    

Swissprot：    Q71DI3    

WB Predicted band size：    15.4kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human,Mouse,Rat    

Immunogen：    Synthesized peptide fragment of human HH3 (AA: 121-136) expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000