This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]

Aliases：    ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1    

Entrez GeneID：    4072    

Swissprot ：   P16422    

WB Predicted band size：    35kDa    

Host/Isotype ：   Mouse IgG2a    

Species Reactivity ：   Human,Mouse,Rat,Monkey    

Immunogen ：   Purified recombinant fragment of human EPCAM (AA: extra(116-265)) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200-1/1000    

FCM    1/200-1/400    

ELISA    1/10000