AccuSift provides high‑performance insulin‑like growth factor 1 antibody pairings, characterized by exceptional batch‑to‑batch consistency and optimized for IVD kit development (Lateral Flow, Chemiluminescence, ELISA, POCT). These pairings offer high affinity and specificity, facilitating rapid detection.Insulin‑like growth factor 1 (IGF‑1) is a single‑chain polypeptide encoded by the human IGF1 gene. Its secretion is mainly regulated by growth hormone, with the liver being the primary synthesis organ. The protein activates signaling pathways such as PI3K‑AKT and Ras‑MAPK through the IGF‑1 receptor, playing a central role in skeletal growth, muscle protein synthesis, glycogen regulation, and neural development.Clinically, IGF‑1 measurement is used to evaluate growth hormone disorders, diabetic metabolic status, and tumor malignancy. Studies show that abnormal IGF‑1 levels are associated with conditions such as acromegaly and atherosclerosis, and it participates in the functional regulation of endothelial cells in vitro in blood‑brain barrier models.Performance Characteristics:
•Source: Mouse Monoclonal Antibody
•Purity: ≥ 90%
•Recommended Pairing: (Coating) / (Labeling)
•Storage: Long‑term storage at ≤ –20°C; short‑term storage at 2–8°C. Shipped on ice packs.
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