Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP_002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Aliases：    CK8; CYK8; K2C8; KRT8    

Entrez GeneID：    3856    

Swissprot ：   P05787    

WB Predicted band size：    54kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity：    Human,Mouse    

Immunogen：    Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

IF/ICC    1/200 - 1/1000    

ELISA    1/10000