This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome.
Aliases : ACTSA;α-Smooth Muscle Actin;Alpha-actin-2;Alpha actin 2
Entrez GeneID: 59
Swissprot : P62736
WB Predicted band size: 42kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human, Mouse, Rat
Immunogen: Purified recombinant fragment of human ACTA2 (AA: 2-124) expressed in E. Coli.
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