This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.

Aliases：    ERF; ETF1; ERF1; TB3-1; D5S1995; SUP45L1    

Entrez GeneID：    2107    

Swissprot：    P62495    

WB Predicted band size：    49kDa    

Host/Isotype：   Mouse IgG1    

Species Reactivity ：   Human    

Immunogen：    Purified recombinant fragment of human RF1 (AA: 288-437) expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000