The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Aliases ：   CANP; muCL; CANP1; SPG76; CANPL1; muCANP    

Entrez GeneID：    823    

Swissprot ：   P07384     

WB Predicted band size：    81.9kDa    

Host/Isotype ：  Mouse IgG1    

Species Reactivity ：   Human    

Immunogen ：   Purified recombinant fragment of human CAPN1 (AA: 501-714) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000