Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Aliases : BTF2; BT2.2; BTN2.2
Entrez GeneID: 10385
Swissprot : Q8WVV5
WB Predicted band size: 59kDa
Host/Isotype: Mouse IgG2a
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human BTN2A2 (AA: extra 57-237) expressed in E. Coli.