This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases :  VTCN1; B7X; B7S1; B7-H4; B7h.5; VCTN1; PRO1291    

Entrez GeneID :   79679    

Swissprot :   Q7Z7D3    

WB Predicted band size :  30.9kDa    

Host/Isotype :  Mouse IgG1     

Species Reactivity :  Human    

Immunogen :  Purified recombinant fragment of human B7H4 (AA: extra 25-259) expressed in HEK293 cells.    

FCM    1/200 - 1/400    

ELISA    1/10000