This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases : VTCN1; B7X; B7S1; B7-H4; B7h.5; VCTN1; PRO1291
Entrez GeneID: 79679
Swissprot : Q7Z7D3
WB Predicted band size : 30.9kDa
Host/Isotype : Mouse IgG1
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human B7H4 (AA: extra 25-259) expressed in HEK293 cells.