The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Aliases: AIK; ARK1; AURA; BTAK; STK6; STK7; STK15; PPP1R47
Entrez GeneID : 6790
Swissprot: O14965
WB Predicted band size : 45.8kDa
Host/Isotype : Mouse IgG1
Species Reactivity : Human,Mouse
Immunogen: Purified recombinant fragment of human AURKA (AA: 268-404) expressed in E. Coli.