This gene encodes a ubiquitin-like-conjugating enzyme and is a component of ubiquitination-like systems involved in autophagy, the process of degradation, turnover and recycling of cytoplasmic constituents in eukaryotic cells. This protein is known to play a role in regulation of autophagy during cell death. A pseudogene of this gene is located on chromosome 20. Alternative splicing results in multiple transcript variants encoding different isoforms.
Aliases : APG3; APG3L; PC3-96; APG3-LIKE
Entrez GeneID : 64422
Swissprot : Q9NT62
WB Predicted band size : 35.9kDa
Host/Isotype : Mouse IgG1
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human ATG3 (AA: 1-100) expressed in E. Coli.