The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene.

Aliases :   PM227; AHNAKRS    

Entrez GeneID:    79026    

Swissprot:    Q09666    

WB Predicted band size:    63KDa    

Host/Isotype :   Mouse IgG1    

Species Reactivity :   Human    

Immunogen:    Purified recombinant fragment of human AHNAK (AA: 1-200) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000