AccuSift provides high-performance Sulfa synergistagent Competitive Antibody Pair, characterized by exceptional batch-to-batch consistency and optimized for IVD kit development (Lateral Flow, Chemiluminescence, ELISA, POCT). These pairings offer high affinity and specificity, facilitating rapid detection.Sulfonamide potentiators are a class of compounds that, when used in combination with sulfonamide drugs, significantly enhance antibacterial activity. Their core mechanism of action involves the dual blockade of the bacterial folic acid metabolic pathway. By inhibiting dihydrofolate reductase (e.g., Trimethoprim/TMP) or protecting sulfonamides from degradation (e.g., β-lactamase inhibitors), they synergistically block two key steps in bacterial folic acid synthesis, turning a bacteriostatic effect into a bactericidal one.Performance Characteristics:
•Sensitivity: ELISA IC50: 0.5 ppb; Colloidal Gold Visual Cut-off: 5 ppb
•Cross-Reactivity: Trimethoprim (TMP) 1 ppb, Diaveridine (DVD) 1 ppb, Ormetoprim (OMP) 2 ppb
•Source: Mouse Monoclonal Antibody
•Purity: ≥ 90%
•Recommended Pairing: (Coating) / (Labeling)
•Storage: Long-term storage at ≤ -20°C; short-term storage at 2-8°C. Shipped on ice packs.