TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Aliases：    PSCTK4    

Entrez GeneID：    7006    

Swissprot：    P42680    

WB Predicted band size：    74kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human, Mouse    

Immunogen：    Purified recombinant fragment of TEC expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000