Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Tissue specificity: Widely expressed with high level in liver.
Aliases: OCT1; HOCT1; oct1_cds; SLC22A1
Entrez GeneID: 6580
Swissprot: O15245
WB Predicted band size: 61.2kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human SLC22A1 expressed in E. Coli.