The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants.

Aliases：    RST; OAT4L; URAT1    

Entrez GeneID：    116085    

Swissprot：    Q96S37    

WB Predicted band size：    59.6kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human, Mouse    

Immunogen：    Purified recombinant fragment of human SLC22A12 (AA: 30-145) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000