This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

Aliases：    TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1    

Entrez GeneID：    6402    

Swissprot：    P14151      

WB Predicted band size：    42.2kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivit：    Human    

Immunogen：   Purified recombinant fragment of human SELL (AA: 83-186) expressed in E. Coli.    

IF/ICC    1/200 - 1/1000    

ELISA    1/10000