This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008]

Aliases:    NEUROD1; BETA2; BHF-1; MODY6; bHLHa3    

Entrez GeneID:    4760    

Swissprot:    Q13562    

WB Predicted band size:    40kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity:    Human    

Immunogen :   Purified recombinant fragment of human Neurod (AA: 26-91) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000