This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]

Aliases：    HEC; HEC1; TID3; KNTC2; HsHec1; hsNDC80    

Entrez GeneID：   10403    

Swissprot ：   O14777     

WB Predicted band size：    74kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity：    Human    

Immunogen ：   Purified recombinant fragment of human NDC80 (AA: 443-642) expressed in Mammalian.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000