This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.

Aliases :   HEC; HEC1; TID3; KNTC2; HsHec1; hsNDC80    

Entrez GeneID :   10403    

Swissprot:    O14777    

WB Predicted band size :   74KDa    

Host/Isotype:    Mouse IgG2a    

Species Reactivity:    Human    

Immunogen:    Purified recombinant fragment of human NDC80 (AA: 443-642) expressed in mammalian cells.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000