MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
Aliases: LC3; LC3A; ATG8E; MAP1ALC3; MAP1BLC3
Entrez GeneID : 84557
Swissprot : Q9H492
WB Predicted band size: 14.3kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human MAP1LC3A (AA: 1-121) expressed in E. Coli.