This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.

Aliases：    SMPR; MPR46; CD-MPR; MPR 46; MPR-46; CD-M6PR    

Entrez GeneID：    4074    

Swissprot：    P20645      

WB Predicted band size：    30.9kDa    

Host/Isotype：    Mouse IgG2b    

Species Reactivity ：   Human, Mouse    

Immunogen：    Purified recombinant fragment of human M6PR (AA: 124-277) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000