This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Aliases ： JTK10; THCYT3
Entrez GeneID： 3717
Swissprot ： O60674
WB Predicted band size： 130.7kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human JAK2 (AA: 745-955) expressed in E. Coli.
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