This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Aliases ：   JTK10; JAK2    

Entrez GeneID：    3717    

Swissprot ：   O60674      

WB Predicted band size ：   130.6kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity ：   Human    

Immunogen ：   Purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.    

WB    1/500 - 1/2000    

ELISA    1/10000