This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

Aliases ：   HD2; RPD3; YAF1    

Entrez GeneID：    3066    

Swissprot：    Q92769        

WB Predicted band size：    55.4kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity ：   Human,Mouse,Monkey,Rat    

Immunogen：    Purified recombinant fragment of human HDAC2 (AA: 217-327) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000