This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Aliases : IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha; CHUK
Entrez GeneID: 1147
Swissprot: O15111
WB Predicted band size: 85kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human CHUK expressed in E. Coli.