The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.

Aliases ：   CD40LG; IGM; IMD3; TRAP; gp39; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L    

Entrez GeneID ：   959    

Swissprot：    P29965    

WB Predicted band size：    29.3kDa    

Host/Isotype：    Mouse IgG1     

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human CD154 (AA: extra 47-261) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000