The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
Aliases: CD40LG; IGM; IMD3; TRAP; gp39; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L
Entrez GeneID: 959
Swissprot: P29965
WB Predicted band size: 29.3kDa
Host/Isotype: Mouse IgG2a
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human CD154 (AA: extra 47-261) expressed in E. Coli.