The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
Aliases: IL7R; ILRA; IL7RA; CDW127; IL-7R-alpha
Entrez GeneID: 3575
Swissprot: P16871
WB Predicted band size : 51.6kDa
Host/Isotype: Mouse IgG2b
Species Reactivity : Human
Immunogen: Purified recombinant fragment of human CD127 (AA: extra 21-239) expressed in E. Coli.